Musk disclosed on the eve of the launch that he “most likely” has a moderate case of coronavirus, despite mixed results. He was replaced in his official duties at Kennedy Space Center by SpaceX President Gwynne Shotwell. She joined NASA Administrator Jim Bridenstine for last-minute remarks and photos with the astronauts prior to launch.
The SpaceX chief tweeted a heart shortly after launch.
The Crew Dragon spacecraft lifted off from Launch Complex 39A at 7:27 p.m. ET Sunday.
The six-month mission is the first crew rotation flight on a U.S. commercial spacecraft.
The Crew-1 mission is transporting NASA astronauts Mike Hopkins, Victor Glover and Shannon Walker and Japan Aerospace Exploration Agency astronaut Soichi Noguchi to the International Space Station aboard the Crew Dragon vehicle. It follows a successful Demo-2 mission with SpaceX earlier this year.
The Associated Press contributed to this article.